Link to register to this course
ENS 46 rue d’Ulm, 75005. Third floor. Bring your laptop for the practicals.
Monday October 3, 9-12h: Genetics and the Genotype-Phenotype Relationship (Course), Mapping the genes underlying phenotypic variation (Course)
Monday October 3, 14h-17h: Gephebase (Course and Practicals), The Loci of Insect Evolution (Homework)
For Oct 10, please do the Genetics Exercices (pages 1-2 of this document).
Monday October 10, 9-12h: Manipulating DNA, CRISPR and gene drive (Course)
Monday October 10, 14h-17h: Correction of the Genetics Exercices, Interactions between several loci, Epistasis, Super Genes, Pleiotropy (Course)
For Oct 17, prepare a 5-min presentation on one topic related to “The Loci of Insect Evolution”. Include your graph/table and name in the Homework Google Document.
Monday October 17, 9h-10h30: The Loci of Insect Evolution – Student Presentations and Discussion – Part I
Monday October 17, 10h30-12h: Genetic screens, Noise, Cryptic Variation, Robustness, Quantitative Genetics (Course)
Monday October 17, 14h-15h: The Loci of Insect Evolution – Student Presentations and Discussion – Part II
Monday October 17, 15h-17h: Phylogenetic trees and their interpretations (Course, Practicals, Correction)
For Oct 24, please read “Gene editing is not “precision breeding” and the term is misleading” and prepare several arguments for/against using the term “precision breeding”.
Monday October 24, 9h-11h30: The Genetic Basis of Phenotypic Plasticity (Course Jean-Michel Gibert) on Zoom (link).
Monday October 24, 11h30-12h: Discussion on “Gene editing is not “precision breeding” and the term is misleading”
Monday October 24, 14h-16h: Hugues Roest-Crollius course (on Zoom, see Moodle)
Wednesday October 26, 9h-12h: Analysis of Experimental Data: Coat Color in Snowshoe hares
Thursday November 17, 14h-17h: Exam, no documents allowed.
2021 – Pigmentation in canaries (with correction)
2020 – Evolution of Drosophila glue (with correction)
2019 – Evolution of ladybirds
2018 – Variation in leaf shape in Capsella
November 2019 PDF Presentations
Genetic bases of phenotypic plasticity (Jean-Michel Gibert)
The Genotype-Phenotype Map for Shape: Insights from Morphogenesis (Alexis Matamoro-Vidal)
Coloration: a great system to study genotype-phenotype relationships (Thibault Lorin)
Various genetics exercices
SARS-CoV-2 sequences Practical
Red and green aphids, polar bears, evolution of lice, Cytochrome b and fungicide resistance (3h) PDF
2020 exercices: polar bears, evolution of lice, Cytochrome b and fungicide resistance PDF
Analysis of experimental data
Evolution of coat color in snowshoe hares
Evolution of polyphenism in the Lepidoptera Manduca sexta
Practicals “Evolution and origins of SARS-CoV-2”
Each student should choose a topic, prepare and present it to the class. SARS-CoV-2 Practicals Text .odt file.
Gephebase practicals 2019: transposable elements in evolutionary changes
Gephebase entries related to transposable elements