Link to register to this course
ENS 46 rue d’Ulm, 75005. Third floor. Bring your laptop for the practicals.
2023
Monday October 2, 9-12h: Genetics and the Genotype-Phenotype Relationship (Course), Mapping the genes underlying phenotypic variation (Course)
Monday October 2, 14h-17h: Gephebase (Course and Practicals), Leaf butterflies (Practical)
For Oct 9, please do the Genetics Exercices (pages 1-2 of this document) and finish the Annals “leaf butterflies“.
Wednesday October 4, 9-12h: Manipulating DNA, CRISPR and gene drive (Course)
Monday October 9, 9h-12h: Correction of the Genetics Exercices, Interactions between several loci, Epistasis, Super Genes, Pleiotropy (Course)
For Oct 16, prepare one slide and a 5-min presentation on one biotechnology. Please choose and indicate your name among the list here or ask the teacher if you would like to present another biotechnology. Include your slide and name in the Google Presentation Document.
For Oct 16, please read also “Gene editing is not “precision breeding” and the term is misleading” and prepare several arguments for/against using the term “precision breeding”.
Monday October 16, 9h-12h: Biotechnologies – Student Presentations and Discussion
Monday October 16, 14h-15h30: Genetic screens, Noise, Cryptic Variation, Robustness, Quantitative Genetics (Course)
Monday October 16, 15h30-17h: Phylogenetic trees and their interpretations (Course, Practicals, Correction)
Monday October 23, 9h-12h: The Genetic Basis of Phenotypic Plasticity (Course Jean-Michel Gibert).
Monday October 23, 14h-17h: Analysis of Experimental Data: Coat Color in Snowshoe hares
3-h Exam, no documents allowed.
2022
Monday October 3, 9-12h: Genetics and the Genotype-Phenotype Relationship (Course), Mapping the genes underlying phenotypic variation (Course)
Monday October 3, 14h-17h: Gephebase (Course and Practicals), The Loci of Insect Evolution (Homework)
For Oct 10, please do the Genetics Exercices (pages 1-2 of this document).
Monday October 10, 9-12h: Manipulating DNA, CRISPR and gene drive (Course)
Monday October 10, 14h-17h: Correction of the Genetics Exercices, Interactions between several loci, Epistasis, Super Genes, Pleiotropy (Course)
For Oct 17, prepare a 5-min presentation on one topic related to “The Loci of Insect Evolution”. Include your graph/table and name in the Homework Google Document.
Monday October 17, 9h-10h30: The Loci of Insect Evolution – Student Presentations and Discussion – Part I
Monday October 17, 10h30-12h: Genetic screens, Noise, Cryptic Variation, Robustness, Quantitative Genetics (Course)
Monday October 17, 14h-15h: The Loci of Insect Evolution – Student Presentations and Discussion – Part II
Monday October 17, 15h-17h: Phylogenetic trees and their interpretations (Course, Practicals, Correction)
For Oct 24, please read “Gene editing is not “precision breeding” and the term is misleading” and prepare several arguments for/against using the term “precision breeding”.
Monday October 24, 9h-11h30: The Genetic Basis of Phenotypic Plasticity (Course Jean-Michel Gibert) on Zoom (link).
Monday October 24, 11h30-12h: Discussion on “Gene editing is not “precision breeding” and the term is misleading”
Monday October 24, 14h-16h: Hugues Roest-Crollius course (on Zoom, see Moodle)
Wednesday October 26, 9h-12h: Analysis of Experimental Data: Coat Color in Snowshoe hares
Thursday November 17, 14h-17h: Exam, no documents allowed.
Annals (1h30 exams)
2022 – Leaf butterflies (with correction)
2021 – Pigmentation in canaries (with correction)
2020 – Evolution of Drosophila glue (with correction)
2019 – Evolution of ladybirds
2018 – Variation in leaf shape in Capsella
November 2019 PDF Presentations
Genetic bases of phenotypic plasticity (Jean-Michel Gibert)
The Genotype-Phenotype Map for Shape: Insights from Morphogenesis (Alexis Matamoro-Vidal)
Coloration: a great system to study genotype-phenotype relationships (Thibault Lorin)
Short exercices
Various genetics exercices
SARS-CoV-2 sequences Practical
Red and green aphids, polar bears, evolution of lice, Cytochrome b and fungicide resistance (3h) PDF
2020 exercices: polar bears, evolution of lice, Cytochrome b and fungicide resistance PDF
Analysis of experimental data
Evolution of coat color in snowshoe hares
Evolution of polyphenism in the Lepidoptera Manduca sexta
Practicals “Evolution and origins of SARS-CoV-2”
Each student should choose a topic, prepare and present it to the class. SARS-CoV-2 Practicals Text .odt file.
Gephebase practicals 2019: transposable elements in evolutionary changes
Google document
Gephebase entries related to transposable elements